Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 08/04/22 16:00 | 08/04/22 16:00 | FC Sevilla | FC Granada | 4:2 | 3 - 6 - 6 |
| 09/04/22 09:00 | 09/04/22 09:00 | FC Cádiz | Real Betis Sevilla | 1:2 | 6 - 5 - 3 |
| 09/04/22 11:15 | 09/04/22 11:15 | RCD Mallorca | Atlético Madrid | 1:0 | 6 - 6 - 3 |
| 09/04/22 13:30 | 09/04/22 13:30 | FC Villarreal | Athletic Bilbao | 1:1 | 3 - 6 - 4 |
| 09/04/22 16:00 | 09/04/22 16:00 | Real Madrid | FC Getafe | 2:0 | 3 - 6 - 6 |
| 10/04/22 09:00 | 10/04/22 09:00 | CA Osasuna | Deportivo Alavés | 1:0 | 3 - 6 - 6 |
| 10/04/22 11:15 | 10/04/22 11:15 | Espanyol Barcelona | Celta Vigo | 1:0 | 3 - 4 - 6 |
| 10/04/22 13:30 | 10/04/22 13:30 | FC Elche | Real Sociedad | 1:2 | 6 - 5 - 3 |
| 10/04/22 16:00 | 10/04/22 16:00 | UD Levante | FC Barcelona | 2:3 | 6 - 6 - 3 |
| 11/04/22 16:00 | 11/04/22 16:00 | Rayo Vallecano | FC Valencia | 1:1 | 4 - 5 - 4 |