Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 15/04/22 16:00 | 15/04/22 16:00 | Real Sociedad | Real Betis Sevilla | 0:0 | 3 - 5 - 6 |
| 16/04/22 09:00 | 16/04/22 09:00 | FC Elche | RCD Mallorca | 3:0 | 3 - 5 - 6 |
| 16/04/22 11:15 | 16/04/22 11:15 | Deportivo Alavés | Rayo Vallecano | 1:0 | 4 - 6 - 4 |
| 16/04/22 13:30 | 16/04/22 13:30 | FC Valencia | CA Osasuna | 1:2 | 3 - 6 - 6 |
| 16/04/22 16:00 | 16/04/22 16:00 | FC Getafe | FC Villarreal | 1:2 | 5 - 6 - 3 |
| 17/04/22 09:00 | 17/04/22 09:00 | FC Granada | UD Levante | 1:4 | 4 - 5 - 5 |
| 17/04/22 11:15 | 17/04/22 11:15 | Atlético Madrid | Espanyol Barcelona | 2:1 | 3 - 6 - 6 |
| 17/04/22 13:30 | 17/04/22 13:30 | Athletic Bilbao | Celta Vigo | 0:2 | 4 - 5 - 5 |
| 17/04/22 16:00 | 17/04/22 16:00 | FC Sevilla | Real Madrid | 2:3 | 6 - 4 - 3 |
| 18/04/22 16:00 | 18/04/22 16:00 | FC Barcelona | FC Cádiz | 0:1 | 3 - 6 - 6 |