| Eastern Conference | Jo | Pts | Gols | Dif | V | E | D | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 27 | 60 | 55:21 | 34 | 18 | 6 | 3 |
| 2. | Inter Miami CF | 27 | 46 | 64:50 | 14 | 12 | 10 | 5 |
| 3. | New England Revolution | 27 | 46 | 45:36 | 9 | 14 | 4 | 9 |
| 4. | Charlotte FC | 27 | 43 | 47:38 | 9 | 12 | 7 | 8 |
| 5. | Chicago Fire | 26 | 42 | 46:38 | 8 | 12 | 6 | 8 |
| 6. | Philadelphia Union | 27 | 39 | 54:44 | 10 | 11 | 6 | 10 |
| 7. | Orlando City | 27 | 34 | 48:64 | -16 | 10 | 4 | 13 |
| 8. | New York City FC | 27 | 33 | 41:36 | 5 | 8 | 9 | 10 |
| 9. | Cincinnati FC | 26 | 33 | 55:64 | -9 | 8 | 9 | 9 |
| 10. | New York Red Bulls | 27 | 33 | 34:51 | -17 | 9 | 6 | 12 |
| 11. | DC United | 26 | 30 | 34:42 | -8 | 6 | 12 | 8 |
| 12. | Columbus Crew | 27 | 29 | 39:43 | -4 | 8 | 5 | 14 |
| 13. | Toronto FC | 27 | 29 | 39:51 | -12 | 6 | 11 | 10 |
| 14. | Atlanta United FC | 27 | 27 | 32:45 | -13 | 7 | 6 | 14 |
| 15. | CF Montreal | 27 | 24 | 34:54 | -20 | 6 | 6 | 15 |
| Western Conference | Jo | Pts | Gols | Dif | V | E | D | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 26 | 50 | 59:26 | 33 | 15 | 5 | 6 |
| 2. | St. Louis City SC | 27 | 47 | 48:36 | 12 | 13 | 8 | 6 |
| 3. | FC Dallas | 27 | 47 | 50:42 | 8 | 13 | 8 | 6 |
| 4. | San Jose Earthquakes | 27 | 45 | 49:39 | 10 | 13 | 6 | 8 |
| 5. | Houston Dynamo | 27 | 44 | 34:32 | 2 | 13 | 5 | 9 |
| 6. | Los Angeles FC | 28 | 41 | 43:30 | 13 | 11 | 8 | 9 |
| 7. | Seattle Sounders | 27 | 38 | 35:35 | 0 | 10 | 8 | 9 |
| 8. | Colorado Rapids | 27 | 36 | 38:38 | 0 | 11 | 3 | 13 |
| 9. | Los Angeles Galaxy | 28 | 36 | 37:44 | -7 | 9 | 9 | 10 |
| 10. | San Diego FC | 27 | 32 | 47:47 | 0 | 8 | 8 | 11 |
| 11. | Portland Timbers | 27 | 32 | 48:51 | -3 | 9 | 5 | 13 |
| 12. | Real Salt Lake | 27 | 32 | 40:44 | -4 | 9 | 5 | 13 |
| 13. | Austin FC | 27 | 31 | 35:47 | -12 | 7 | 10 | 10 |
| 14. | Minnesota United FC | 27 | 29 | 40:49 | -9 | 7 | 8 | 12 |
| 15. | Sporting Kansas City | 27 | 21 | 32:65 | -33 | 6 | 3 | 18 |