| Jo | Pts | Gols | Dif | V | E | D | ||
|---|---|---|---|---|---|---|---|---|
| 1. | Cincinnati FC | 21 | 42 | 33:27 | 6 | 13 | 3 | 5 |
| 2. | Nashville SC | 21 | 41 | 37:23 | 14 | 12 | 5 | 4 |
| 3. | Philadelphia Union | 21 | 40 | 35:21 | 14 | 12 | 4 | 5 |
| 4. | San Diego FC | 21 | 39 | 44:29 | 15 | 12 | 3 | 6 |
| 5. | Vancouver Whitecaps | 20 | 38 | 35:22 | 13 | 11 | 5 | 4 |
| 6. | Columbus Crew | 21 | 38 | 34:27 | 7 | 10 | 8 | 3 |
| 7. | Minnesota United FC | 21 | 37 | 35:24 | 11 | 10 | 7 | 4 |
| 8. | Inter Miami CF | 18 | 35 | 42:29 | 13 | 10 | 5 | 3 |
| 9. | Orlando City | 21 | 34 | 39:28 | 11 | 9 | 7 | 5 |
| 10. | Portland Timbers | 20 | 33 | 30:28 | 2 | 9 | 6 | 5 |
| 11. | New York City FC | 20 | 31 | 27:22 | 5 | 9 | 4 | 7 |
| 12. | New York Red Bulls | 21 | 30 | 33:25 | 8 | 8 | 6 | 7 |
| 13. | Seattle Sounders | 20 | 30 | 28:26 | 2 | 8 | 6 | 6 |
| 14. | Los Angeles FC | 18 | 29 | 33:24 | 9 | 8 | 5 | 5 |
| 15. | San Jose Earthquakes | 21 | 28 | 41:33 | 8 | 7 | 7 | 7 |
| 16. | Chicago Fire | 20 | 28 | 39:36 | 3 | 8 | 4 | 8 |
| 17. | Charlotte FC | 21 | 26 | 34:36 | -2 | 8 | 2 | 11 |
| 18. | Houston Dynamo | 21 | 26 | 29:34 | -5 | 7 | 5 | 9 |
| 19. | Austin FC | 20 | 26 | 15:23 | -8 | 7 | 5 | 8 |
| 20. | Colorado Rapids | 22 | 26 | 24:33 | -9 | 7 | 5 | 10 |
| 21. | New England Revolution | 20 | 24 | 26:25 | 1 | 6 | 6 | 8 |
| 22. | Sporting Kansas City | 21 | 23 | 33:38 | -5 | 6 | 5 | 10 |
| 23. | Real Salt Lake | 20 | 22 | 22:28 | -6 | 6 | 4 | 10 |
| 24. | FC Dallas | 20 | 21 | 27:37 | -10 | 5 | 6 | 9 |
| 25. | DC United | 21 | 19 | 17:39 | -22 | 4 | 7 | 10 |
| 26. | Atlanta United FC | 20 | 18 | 22:37 | -15 | 4 | 6 | 10 |
| 27. | Toronto FC | 20 | 17 | 23:28 | -5 | 4 | 5 | 11 |
| 28. | St. Louis City SC | 21 | 15 | 21:34 | -13 | 3 | 6 | 12 |
| 29. | CF Montreal | 21 | 14 | 18:40 | -22 | 3 | 5 | 13 |
| 30. | Los Angeles Galaxy | 21 | 12 | 22:42 | -20 | 2 | 6 | 13 |